Cardiovascular diseases (CVDs) are the main cause of mortality in Poland.1 Like other Central and Eastern European countries, Poland has a high CVD risk, with high premature CVD mortality.2 Recent data from the European Commission indicated that in 2016 the standardized CVD death rate per 100000 men aged 25 to 64 years in Poland reached 125, while in Germany, it was 60; in the United Kingdom, 58; and in the Netherlands, only 32.3 Although Poland has experienced a steady decrease in CVD mortality rates since the 1990s, it is still considerably higher than the European Union average.4 Recent research has suggested that a decrease of 50% in CVD mortality observed between 1991 and 2005 was mainly attributable to favorable lifestyle changes (eg, a decrease in cholesterol levels, improved control of hypertension, and decreased prevalence of active smoking).5 Comparable studies conducted in other countries showed similar patterns, with a reduction of approximately 50% in CVD mortality.6 Taken together, modifying these CVD risk factors via public policy interventions may have a beneficial effect at the population level.
The link between active smoking and the development of CVD is well established. For example, a recently published meta-analysis of 141 cohort studies has shown that smoking even 1 cigarette a day is associated with an increase of nearly 50% and 57% in CVD risk in men and women, respectively.7 Moreover, there is growing evidence that second-hand smoke is also one of the major contributors to CVD mortality, and it was estimated to increase the risk of acute myocardial infarction (AMI) by 30%.8 The evidence on the impact of a reduction in tobacco smoke exposure on AMI admissions is diverse.9-11 The results differ with respect to the timing of the effects (rapid or only long-term) and range from nonsignificant reductions10 to reductions by even up to 47% in AMI admissions.11
In Poland, a public smoking ban was introduced on November 15, 2010, leading to a marked decrease in tobacco smoke exposure in public places.12 The largest, more than twofold, reduction was recorded in gastronomic and entertainment facilities (from 36% in 2009 to 14% in 2011).12 Therefore, it would be reasonable to expect a decrease in hospital admissions due to AMI and in CVD mortality rates in the years following the ban. Because of a high CVD burden in the Eastern European countries and lack of such data, there is a high need for this analysis. Thus, we aimed to assess the hospitalization rates for AMI in Poland before and after the introduction of the smoking ban in public places with regard to age, sex, and the place of residence.
Patients and methods
We searched the Polish nationwide Acute Myocardial Infarction Database (AMI-PL) for all cases of AMI that occurred between 2009 and 2014. The design of AMI-PL has been described earlier.13 In brief, the database contains the record of all AMI cases provided by the National Health Fund, the sole public and compulsory health insurer in Poland. The National Health Fund has signed contracts with private and public healthcare providers and it is the only payer of medical procedures. Therefore, it provides unified electronic nationwide data on medical procedures and disease incidence. The AMI cases are selected based on a primary diagnosis coded in the International Classification of Diseases, Tenth Revision as I21 or I22, irrespective of any AMI occurrence in the past.
We analyzed the number of hospital admissions for AMI in subsequent years in the general population before (2009–2010) and after (2011–2014) the introduction of the smoking ban in Poland in November 2010. Given that the ban was introduced as late as in November, the year 2010 was classified together with 2009 as the one preceding the smoking ban. The years 2011–2014 were divided into 2-year periods: short-term (2011–2012) and long-term (2013–2014) to search for temporal trends. We also analyzed prespecified subgroups, based on patients’ sex, age (20–64 years vs 65 years or older), and place of residence (rural [<2000 people] vs urban [2000 to <100000 people, 100000–200000 people, 200000–500000 people, and >500000 people]). There were no specific exclusion criteria. The study did not require approval by an ethics committee.
To eliminate a possible effect of changes in the age structure of the Polish population over time, we calculated age-standardized hospitalization rates applying to the age structure of the total Polish population in the period 2013 to 2014 as standard (the same for men and women to enable a comparison of sex differences in rates and trends). The age-standardized hospitalization rates were presented together with confidence intervals (CIs). We considered the differences between the rates to be significant when 95% CIs were not overlapping. Crude numbers of hospitalizations due to AMI in the subsequent years were also provided for the whole population and for both age groups.
In the years 2009 to 2010, before the introduction of the smoking ban, the average number of hospitalizations due to AMI in Poland in patients aged 20 years or older was 79323. In the subsequent years, the hospitalization rate initially increased (2011–2012), but then decreased (2013–2014), with the average number of hospitalizations of 80783 and 77356, respectively. Between the years before the introduction of the smoking ban (2009–2010) and in the subsequent period (2013–2014), a reduction in the number of AMI hospitalizations was observed in both age groups (Figure 1).
In both sexes and age groups, the age-standardized hospitalization rates for AMI decreased only slightly after the 2-year period of 2011 to 2012 but were more visible in the subsequent years (2013–2014) (Figure 2A and 2B).
Following the introduction of the smoking ban, hospitalizations for AMI decreased markedly in both sexes and age groups in the long-term follow-up. Data are presented in Tables 1 and 2. In men, the hospitalization rates decreased in both age groups and in all rural and urban areas (regardless of the number of inhabitants). Moreover, a reduction in the number of AMI hospitalizations in men was already seen in most places of residence in the initial period (2011–2012). However, in younger women (20–64 years), the decline in the rates of AMI hospitalizations was not observed in towns with more than 200000 inhabitants during the whole study. Among older people (>65 years), only in women in large towns (over 500000 inhabitants), no significant decline in the rates of hospitalizations for AMI during the whole study was observed.
|Place of residence (number of residents; rates per 100000)||Age-standardized hospitalization rates for AMI|
Towns (2000 to <100000)
Data are presented as standard ratio (95% CI).
Abbreviations: AMI, acute myocardial infarction
|Place of residence (number of residents; rates per 100000)||Age-standardized hospitalization rates for AMI (confidence intervals)|
Towns (2000 to <100000)
Data are presented as standard ratio (95% CI).
Abbreviations: see Table 1
Our study showed that after the introduction of the smoking ban, the rate of AMI hospitalizations decreased both in men and women as well as both in younger and older patients. The decline occurred mainly in the long-term follow-up. However, it was not significant in female inhabitants of urban areas (>100000 inhabitants).
In contrast to short-term studies, we found no decline in the total number of AMI hospitalizations in the 2-year period (2009–2010) following the ban implementation, as compared with the subsequent period of the years 2011 and 2012. A decrease in the rates of AMI hospitalizations was observed only in the long-term follow-up, when comparing the years 2009–2010 to 2013–2014. Comparable European studies, conducted in England, Spain, and Italy, showed an early significant decrease in the number of hospital admissions due to AMI following public smoking prohibition.14,15 This suggests an immediate impact of a smoking ban on the rate of AMI hospitalizations. In Spain, a reduction in mortality due to AMI was observed already in the first year after the introduction of smoke-free regulations.9
The discrepancies between studies may partly result from different study designs and ways in which smoking bans were applied in different settings. In regions where the bans were implemented as a stepwise process, the findings were inconsistent, showing a low reduction,16 no significant reduction,10 or a significant decrease in admission rates in the year after a complete smoking ban, as in the Danish population.17 In the United States, the New York state introduced partial smoking restrictions in 1989, followed by a comprehensive statewide ban only in 2003. Hospital admissions for AMI were significantly reduced after 2003.16 In countries where smoking ban implementation was a one-step process, long-term (over 1-year) reductions in AMI admissions ranged from 21% to 47%.11,18 In Portugal, a reduction in the rates of AMI admissions was still observed even after 7 years, which was also attributed to the introduction of a smoking ban.19 Notably, Sargent et al20 reported an increase in the rate of AMI admissions following the revoking of the ban. In general, total smoking bans were shown to be more effective than partial restrictions.21
In Poland, in the years 2009 to 2014, a decrease in the total number of tobacco smokers from 29.2% to 26.1% was previously demonstrated.22 The second-hand smoke exposure in Poland also decreased significantly in public places from 36% in 2009 to 12% in 2011,12 which could translate into decreased rates of AMI hospitalizations. A recent systematic review of 21 studies showed that educational programs, clinician-related factors (such as time to provide counseling), and smoking bans were related to smoking cessation among smokers.23 In a population-based study conducted in Geneva (Switzerland), a significant decrease in the rate of smokers after implementation of a public smoking ban was observed. However, the decrease was only temporal and coincided with a subsequent increase in the number of active smokers.24
Lee et al25 found that the second-hand smoke exposure was associated with smoke-free laws and not with an urban or rural setting. This may result from the positive effect of actions aimed to improve public awareness of the adverse effects of smoking. In our study, the total rates of AMI hospitalizations decreased markedly in both sexes and age groups. However, a long-term decline in the rates of AMI hospitalizations was observed almost in the entire country, except for people living in bigger towns (>200000 and >500000 inhabitants for women and men, respectively). These results are in line with other studies that showed a higher reduction in the rate of AMI admissions in men.26 In Portugal, the effect of the smoking ban was greater in men and in people aged 65 years or older.19 In England, after the introduction of smoke-free laws, the rate of AMI hospitalizations was significantly reduced in individuals aged 60 years or older (both men and women) as well as in men, but not women, younger than 60 years.14 In a mathematical model, Richiardi et al27 also showed that the impact of smoke-free laws on the rate of AMI hospitalizations was lower in women (2.4%–7.2%) than in men (3.6%–10.9%). This might indicate a considerable continued exposure to tobacco smoke in large towns and the need for further antitobacco campaigns, focused especially on younger women.
A long-term decline in the rates of AMI hospitalizations could be confounded by reductions in other major cardiovascular risk factors, such as a decrease in mean cholesterol levels, improvement of blood pressure control, or reduction of active smoking.28-30 There are numerous factors at the individual and organizational levels that may influence smokers’ compliance with a smoking ban, such as personal attitudes or levels of nicotine dependence. Changes in other risk factors might have also impacted the reduction of hospitalization rates observed during the years 2009 to 2014. In Poland, the incidence of CVD remains excessively high compared with other European countries, which may influence the effects of public smoking bans.22
Several limitations of this study have to be acknowledged. First, as noted above, to assess the long-term impact of smoking ban implementation on the rates of AMI hospitalizations, other cardiovascular risk factors should be identified and considered. However, in Poland, cardiovascular risk factors are assessed within 5- to 10-year periods, and such assessments were not carried out at the time of the study. Nevertheless, during the study, no new legal regulations or national programs for prevention of cardiovascular risk factors were introduced. Second, in order to observe trends in the number of hospitalizations due to AMI, a longer period before the introduction of the smoking ban would have to be considered, while the AMI-PL database was started only in 2009. Finally, we could not assess changes in active smoking behaviors following the smoking ban. As we could not analyze the smoking status of our group, we could not assess the effect of the ban on smokers in comparison with nonsmokers. Previous studies have shown that nonsmokers might benefit more from public smoking bans than smokers.31
In conclusion, after the introduction of the smoking ban in public places in Poland in November 2010, the rate of age-standardized AMI hospitalizations decreased markedly in the long-term follow-up both in men and women as well as both in younger and older individuals. The reduction in the rates of AMI hospitalizations differed by the place of residence. No decrease in the rates of AMI hospitalizations was observed in the first 2 years following the introduction of the smoking ban.
Krzysztof Ozierański, MD, 1st Department of Cardiology, Medical University of Warsaw, ul. Banacha 1a, 02-097 Warszawa, Poland, phone: +48225991958, email: email@example.com
April 11, 2019.
May 28, 2019.
June 6, 2019.
KO, AW, BW, MG, TZ, JS, MG, LP, and GO contributed to the concept and design of the study as well as to the acquisition, analysis, and interpretation of the data. KO and AW drafted the manuscript. BW, MG, TZ, JS, MG, LP, and GO critically revised the manuscript. All authors approved the final version of the manuscript and agreed to be accountable for all aspects of the work, ensuring its integrity and accuracy.
Ozierański K, Witkowska A, Wojtyniak B, et al. Smoking ban in public places and myocardial infarction hospitalizations in a European country with high cardiovascular risk: insights from the Polish nationwide AMI-PL database. Pol Arch Intern Med. 2019; 129: 386-391. doi:10.20452/pamw.14862
- Zdrojewski T, Rutkowski M, Bandosz P, et al. Prevalence and control of cardiovascular risk factors in Poland. Assumptions and objectives of the NATPOL 2011 Survey. Kardiol Pol. 2013; 71: 381-392.Crossref
- Piepoli MF, Hoes AW, Agewall S, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts)Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J. 2016; 37: 2315-2381.Crossref
- Cardiovascular diseases. World Health Organization website. http://www.euro.who.int/en/health-topics/noncommunicable-diseases/cardiovascular-diseases/data-and-statistics. Accessed July 10, 2017.
- Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe 2014: epidemiological update. Eur Heart J. 2014; 35: 2950-2459.Crossref
- Bandosz P, O’Flaherty M, Drygas W, et al. Decline in mortality from coronary heart disease in Poland after socioeconomic transformation: modelling study. BMJ. 2012; 344: d8136.Crossref
- Ford ES, Ajani UA, Croft JB, et al. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000. N Engl J Med. 2007; 356: 2388-2398.Crossref
- Hackshaw A, Morris JK, Boniface S, et al. Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports. BMJ. 2018; 360: j5855.Crossref
- Barnoya J, Glantz SA. Cardiovascular effects of secondhand smoke: nearly as large as smoking. Circulation. 2005; 111: 2684-2698.Crossref
- Villalbi JR, Sanchez E, Benet J, et al. The extension of smoke-free areas and acute myocardial infarction mortality: before and after study. BMJ Open. 2011; 1: e000067.Crossref
- Seguret F, Ferreira C, Cambou JP, et al. Changes in hospitalization rates for acute coronary syndrome after a two-phase comprehensive smoking ban. Eur J Prev Cardiol. 2014; 21: 1575-1582.Crossref
- Bartecchi C, Alsever RN, Nevin-Woods C, et al. Reduction in the incidence of acute myocardial infarction associated with a citywide smoking ordinance. Circulation. 2006; 114: 1490-1496.Crossref
- Smoking ban in public places . Ministry of Health website http://www.mz.gov.pl/zdrowie-i-profilaktyka/uzaleznienia/tyton/zakaz-palenia-w-miejscach-publicznych/. Accessed July 15, 2017.
- Gierlotka M, Zdrojewski T, Wojtyniak B, et al. Incidence, treatment, in-hospital mortality and one-year outcomes of acute myocardial infarction in Poland in 2009-2012 - nationwide AMI-PL database. Kardiol Pol. 2015; 73: 142-158.Crossref
- Sims M, Maxwell R, Bauld L, Gilmore A. Short term impact of smoke-free legislation in England: retrospective analysis of hospital admissions for myocardial infarction. BMJ. 2010; 340: c2161.Crossref
- Barone-Adesi F, Vizzini L, Merletti F, Richiardi L. Short-term effects of Italian smoking regulation on rates of hospital admission for acute myocardial infarction. Eur Heart J. 2006; 27: 2468-2472.Crossref
- Juster HR, Loomis BR, Hinman TM, et al. Declines in hospital admissions for acute myocardial infarction in New York state after implementation of a comprehensive smoking ban. Am J Public Health. 2007; 97: 2035-2039.Crossref
- Christensen TM, Moller L, Jorgensen T, Pisinger C. The impact of the Danish smoking ban on hospital admissions for acute myocardial infarction. Eur J Prev Cardiol. 2014; 21: 65-73.Crossref
- Bonetti PO, Trachsel LD, Kuhn MU, et al. Incidence of acute myocardial infarction after implementation of a public smoking ban in Graubunden, Switzerland: two year follow-up. Swiss Med Wkly. 2011; 141: w13206.Crossref
- Abreu D, Sousa P, Matias-Dias C, Pinto FJ. Longitudinal Impact of the Smoking Ban Legislation in Acute Coronary Syndrome Admissions. Biomed Res Int. 2017; 2017: 6956941.Crossref
- Sargent RP, Shepard RM, Glantz SA. Reduced incidence of admissions for myocardial infarction associated with public smoking ban: before and after study. BMJ. 2004; 328: 977-980.Crossref
- Ferrante D, Linetzky B, Virgolini M, et al. Reduction in hospital admissions for acute coronary syndrome after the successful implementation of 100% smoke-free legislation in Argentina: a comparison with partial smoking restrictions. Tob Control. 2012; 21: 402-406.Crossref
- Health Status of Polish Population in 2014. Central Statistical Office website. https://stat.gov.pl/obszary-tematyczne/zdrowie/zdrowie/stan-zdrowia-ludnosci-polski-w-2014-r-,6,6.html. Accessed July 1, 2017.
- Monshi SS1, Halpern MT. Factors associated with smoking cessation and smoking cessation interventions in the Gulf Cooperation Council countries. Saudi Med J. 2019; 40: 119-125.Crossref
- Sandoval JL, Leão T, Cullati S, et al. Public smoking ban and socioeconomic inequalities in smoking prevalence and cessation: a cross-sectional population-based study in Geneva, Switzerland (1995-2014). Tob Control. 2018; 27: 663-669.Crossref
- Lee K, Hwang Y, Hahn EJ, et al. Secondhand smoke exposure is associated with smoke-free laws but not urban/rural status. J Air Waste Manag Assoc. 2015; 65: 624-627.Crossref
- Vasselli S, Papini P, Gaelone D, et al. Reduction incidence of myocardial infarction associated with a national legislative ban on smoking. Minerva Cardioangiol. 2008; 56: 197-203.
- Richiardi L, Vizzini L, Merletti F, Barone-Adesi F. Cardiovascular benefits of smoking regulations: the effect of decreased exposure to passive smoking. Prev Med. 2009; 48: 167-172.Crossref
- Bandosz P, O’Flaherty M, Rutkowski M, et al. A victory for statins or a defeat for diet policies? Cholesterol falls in Poland in the past decade: a modeling study. Int J Cardiol. 2015; 185: 313-319.Crossref
- Khan AA, Chung MJ, Novak E, et al. The long-term risk of smoking in diabetic patients with stable ischemic heart disease treated with intensive medical therapy and lifestyle modification. Eur J Prev Cardiol. 2017; 24: 1506-1514.Crossref
- Carlsson AC, Arnlov J, Sundstrom J, et al. Physical activity, obesity and risk of cardiovascular disease in middle-aged men during a median of 30 years of follow-up. Eur J Prev Cardiol. 2016; 23: 359-65.Crossref
- Cronin EM, Kearney PM, Kearney PP, et al; Coronary Heart Attack Ireland Registry Working Group. Impact of a national smoking ban on hospital admission for acute coronary syndromes: a longitudinal study. Clin Cardiol. 2012; 35: 205-209.Crossref