The current issue of Przegląd Lekarski – Jagiellonian Medical Review (PL-JMR) reflects both the journal’s deep historical legacy and its modern scientific breadth, spanning from translational neuroscience to public health, advanced surgery, and emergency diagnostics. Together, these contributions exemplify the renewed mission of PL-JMR as a platform for integrating tradition, interdisciplinary science, and clinical applicability.

The opening article by Professor Igor Gościński and colleagues1 traces the evolution of Przegląd Lekarski from its founding by Krakow physicians in 1862 into its modern electronic rebirth in 2025. This historical perspective situates the journal within the heritage of the Krakow Medical Society and the Faculty of Medicine of the Jagiellonian University Medical College, emphasizing their close academic partnership. The revival of the journal symbolizes a broader effort to sustain medical scholarship while aligning with contemporary standards of open science and digital publishing.

In the following original research, Krzyściak et al2 present a technically-advanced magnetic resonance spectroscopy study of the anterior and posterior cingulate cortex in schizophrenia. The authors describe region-specific, echo-time–dependent alterations in glutamate-based metabolite ratios and their correlations with depressive and anxiety symptomatology. The study underscores how subtle neurometabolic differences mirror the heterogeneity of emotional dysregulation in schizophrenia, and illustrates the potential of spectroscopy as a biomarker-oriented diagnostic tool.

Żyłka and colleagues3 investigate the relationship between body composition indicators and high-sensitivity C-reactive protein levels in adolescents aged 15–18 years. The findings of sex-dependent associations indicate that subclinical inflammation may already manifest during late puberty and precede overt metabolic disease. This work fills an important epidemiological gap by providing data from a Central European adolescent cohort, and highlights the value of simple anthropometric markers for early prevention strategies.

The comprehensive review by Brożek et al4 synthesizes the rapidly growing evidence on middle meningeal artery embolization as a minimally-invasive alternative or adjunct in the treatment of chronic subdural hematoma. The authors discuss pathophysiological mechanisms, embolic materials, vascular access innovations, and outcomes of recent clinical trials. The review positions this endovascular approach as a transformative technique likely to reshape neurosurgical practice in an aging population.

In their state-of-the-art overview, Czerwiec and Sobczyk5 examine the integration of point-of-care ultrasound (POCUS) in emergency and prehospital settings. The article outlines validated protocols—from Extended Focused Assessment with Sonography for Trauma (E-FAST) to the novel Cranium, Respiratory, Abdomen, Cardiac Function, and Trauma Integration (CRAFT) algorithm—and discusses implementation barriers, teletransmission, and future applications involving artificial intelligence. The review situates ultrasound as a cornerstone of precision emergency medicine, bridging clinical acumen with technological progress.

Ogorzelec and co-authors6 review the dynamic transition of coronary artery bypass grafting toward minimally-invasive paradigms—off-pump, mini-thoracotomy, totally endoscopic, and hybrid revascularization. The analysis compares outcomes of the mini-invasive approaches with those of conventional on-pump surgery, emphasizing reduced neurological complications, faster recovery, and promising results of hybrid robotic techniques. This synthesis highlights how surgical innovation continuously improves patient safety while preserving long-term efficacy.

Concluding the issue, Mirek and Sobczyk7 present a compelling clinical image of prehospital cardiac tamponade following myocardial rupture, diagnosed by paramedics using handheld ultrasound. The case vividly illustrates the life-saving potential of POCUS in the field and underscores the necessity of structured training for emergency personnel.

Together, these articles reflect the journal’s aim to combine the long-standing academic tradition of the Jagiellonian University Medical College with a forward-looking perspective on translational and technological progress in medicine. Each contribution—whether historical, experimental, or clinical—adds to this goal by linking established scientific foundations with current research and practice.