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Original articles

Control of asthma in adults treated with beclomethasone and formoterol in extrafine particle formulation in a real-life setting in Poland: the CASPER noninterventional, observational trial

Piotr Kuna, Izabela Kupryś-Lipińska, Tomasz Dębowski
DOI: 10.20452/pamw.3111
Published online: September 24, 2015
CCBYNCSACC BY-NC-SA 4.0

Abstract

INTR​ODUCTION

Asthma is one of the most common health problems, and its poor control can seriously

affect patients’ lives.

Objectives:

We assessed the level of asthma control in a real‑life setting in Poland, in outpatients treated

with a beclomethasone and formoterol combination pressurized metered‑dose inhaler (BDP/F‑pMDI).

Patients and methods:

The study lasted for 6 months (3 visits). Patients were aged 18 years or older,

were diagnosed with asthma at least 12 months before the inclusion to the study, and had been using

BDP/F‑pMDI hydrofluoroalkanes (HFA) for a minimum of 2 weeks before the enrollment. Asthma control

was determined in accordance with the criteria of the Global Initiative for Asthma. Patients’ data were

collected during study visits, using unified questionnaires with close‑ended questions.

Results:

During the first visit, 8.6% of the patients had controlled asthma; 27.6%, partly controlled

asthma; and 63.9%, uncontrolled asthma. Poorer control of asthma was observed in men, smokers,

patients with a longer history of asthma, higher body mass index, lower physical activity, shorter treatment

with BDP/F‑pMDI HFA, and inaccurate inhaler technique. After 6 months of therapy, asthma control

improved in 74.2% of the patients; 60.1% of the patients met the criteria of controlled asthma; 31.4%,

of partly controlled asthma; and 8.3%, of uncontrolled asthma.

Conclusions:

The use of BDP/F‑pMDI HFA was effective in the long‑term control of asthma, and one

of the important factors improving treatment outcomes is the training of patients in the correct inhaler

technique.

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