Chest pain is a common reason why patients seek medical consultation. Chest pain can be caused by life‑threatening diseases and requires extensive diagnostic evaluation, especially to exclude acute cardiac pathologies. However, in the case of atypical chest pain with a normal electrocardiogram and serum levels of myocardial necrosis markers with in the reference ranges, non‑cardiac causes of chest pain should be considered. This report describes the case of a 90‑year‑old female patient with recurrent chest pain who was eventually diagnosed with osteoporotic vertebral fractures of the thoracic spine.